For optimal flavor, use ripe, in-season, and organic produce if possible. You can substitute grapefruit with more oranges for less tartness or use frozen blueberries in a pinch, though fresh is preferred. For quicker assembly, buy pre-cut fruit. For a lower-carb option, focus on berries and citrus, limiting higher-sugar fruits like grapes. Chill thoroughly before serving for the best refreshing taste.